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Mining the selective remodeling of dna methylation in ...

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By y quan · 2020 · cited by 6 — 9. 3state key laboratory of space medicine fundamentals and application, ... methylation in body regions with gene expression (figure 1).
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Mining the Selective Remodeling of DNA Methylation in1Promoter Regions to Identify Robust Gene-Level Associations2with Phenotype3Yuan Quan1,2,#,*, Fengji Liang3,#, Yuexing Zhu4, Ying Chen2, Ruifeng Xu1,4Jianghui Xiong2,4,*51School of Computer Science and Technology, Harbin Institute of Technology6Shenzhen Graduate School, Shenzhen, Guangdong, 518055, China.72Lab of Epigenetics and Advanced Health Technology, Space Institute of Southern8China, Shenzhen, Guangdong, 518117, China.93State Key Laboratory of Space Medicine Fundamentals and Application, China10Astronaut Research and Training Center, Beijing, 100094, China.114Aromability Inc., Beijing, 100080, China.1213*Correspondence: Jianghui Xiong ([email protected]), and Yuan Quan14([email protected])15#These authors contributed equally to this work.1617181920212223242526272829Abstract30Epigenetics is an essential biological frontier linking genetics to the environment,31where DNA methylation is one of the most studied epigenetic events....