Loading…
Title

Estrogen depletion induces nacl-sensitive hypertension in ...

Description
By z fang · 2001 · cited by 78 — tion of studies into the physiological role of estrogen in females. ... exposure to the high-nacl diet for 8 wk (from 3 wk of age) increased map to 153.
/0
Full Text
Estrogen depletion induces NaCl-sensitive hypertensionin female spontaneously hypertensive ratsZHIWU FANG,1 SCOTT H. CARLSON,1,2 Y. F. CHEN,2 S. OPARIL,2 AND J. MICHAEL WYSS1,21Department of Cell Biology and 2The Vascular Biology and Hypertension Program of theDepartment of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294-0019Received 23 January 2001; accepted in final form 3 August 2001Fang, Zhiwu, Scott H. Carlson, Y. F. Chen, S. Oparil,and J. Michael Wyss. Estrogen depletion induces NaCl-sensitive hypertension in female spontaneously hypertensiverats. Am J Physiol Regulatory Integrative Comp Physiol 281:R1934–R1939, 2001.—In women, arterial pressure generallyincreases after menopause, but several studies suggest thatwomen who eat large amounts of plant estrogens (phytoestro-gens) experience a slower rise in the incidence of postmeno-pausal hypertension. This suggests that both ovarian hor-mones (principally estrogen) and phytoestrogens may protectat least som...